Clariness and SubjectWell merged to create one of the largest global, full-service patient recruitment providers on the planet. Despite the continuous innovation and global delivery of both companies, the industry continuously reports the need for more global capabilities, more therapeutic area expertise and advanced insights and reporting. That’s why ‘the new Clariness’ is built on the combined expertise, technologies, and patient communities of both, to fill the gaps that has previously held back global patient enrollment.
Enhanced global reach – Our combined global reach has been bolstered through the integration of SubjectWell’s US infrastructure and millions of patients within its community into Clariness’ more established EMEA and APAC enrollment ecosystem.
One enrollment ecosystem – We launched our Clariness Hub, which brings together the capabilities, data, performance metrics, and intelligent patient targeting across both companies into one single enrollment ecosystem.
Solutions for every enrollment challenge – Integrating the enrollment solutions behind the support of 2,500 global studies, we now offer a solutions across the three main enrollment areas of our clients, these are enrollment feasibility, patient recruitment, and engagement and retention.
Injecting a scientific approach to our enrollment strategies – We’ve integrated enrollment feasibility models that have been validated through peer-reviewed publications and industry research into our entire suite of solutions, to deliver even more accurate funnel and enrollment strategies.
Together, we bring sponsors and CROs unmatched reach across 60+ countries, 12,500+ research sites, 400+ indications, and one of the world’s largest patient communities, giving clients the true global partner they have been looking for until now.
We are fully committed to outcome-based pricing; however our patient recruitment models will be more balanced across three key areas: setup and systems, outreach and media, and performance delivery, with full transparency of investment against each stage of our statistically-backedenrollment funnel projections.
Clariness has offered performance-based commercial models long before the merger, this does not change. What has changed is our ability to more accurately forecast our outcome projections, thanks to a larger patient network, richer data, and scientifically validated enrollment feasibility models.
While the Clariness name and brand remains, we have taken a “”best of both”” approach; ClinLife is now one of three enrollment platforms that make the Clariness Hub, which is a true combination of the solutions, expertise and technologies of both companies, Clients who worked with either Clariness or SubjectWell previously, will only gain the benefits of enhanced solutions, more accurate funnels, higher patient quality, expanded global reach and more.
This is also reflected in our senior management team. Our leadership team is comprised of executives from both companies, led under the direction of Jim Corrigan, a new addition to Clariness who brings with him decades of experience in leading newly merged businesses to elevated success. Every department across the business is also equipped talent from both organizations in all our locations.
What sets Clariness apart: Most patient recruitment vendors do one thing well. They have reach, technology, or local expertise in a limited number of regions. Clariness now has all of it, at scale, in one place. Several points separate us from the rest of the market: a truly global footprint with compliant operations, a 15M patient community, unmatched experience and first-party data, with a performance track record of 80%+ of projects delivered in line with contracted promises.
Global reach with local intelligence: 60+ countries, 35+ languages, native-speaking in-market teams who understand cultural nuance. This is not just translation; it is genuine local execution backed by 20 years of building patient communities in markets that are genuinely hard to recruit in. Our international team speak enough languages to converse with >70% of the world’s population.
Recruitment technology built for outcomes, not optics: ClinLife® is the world’s leading patient portal with 15 million+ annual visitors and over 400 indications covered. Combined with SubjectWell’s science-backed models and partnerships with healthcare partners, clients get a platform that is designed to convert, not just attract.
Performance accountability: We do not just generate referrals and move on. Our Enrollment Enablement Team globally follows patients through the funnel, in their language, at the right time, using data to optimize contact timing and channel selection. That is why we can stand behind outcome-based pricing.
Science first: The new Clariness was built around scientific rigor, protocol feasibility, patient pre-screening, indication-specific expertise, and indication-specific recruitment models such as those for oncology. We treat recruitment as a clinical discipline, not a media spray and pray.
One partner, full lifecycle: From feasibility and study start-up through to enrollment, retention, and outcomes. Sponsors no longer need to manage multiple vendors across the enrollment journey. We cover it on a global scale, and accountable end to end.
The honest difference: Anyone can promise patients. We’ve delivered on more than 42,000 promises in the form of patient randomizations.
We deliberately do not lead with a fixed channel mix, because the right mix depends entirely on the indication, geography, patient population, and study design. A rare disease trial in Eastern Europe has a completely different optimal channel strategy to a Type 2 diabetes study in the US. Locking clients into a predefined media model is how recruitment vendors underdeliver.
Clariness operates one of the largest digital patient outreach networks in the industry, combining paid social including Meta and other platforms, search, display, patient communities, condition-specific portals, ClinLife® organic traffic, and partner networks. Meta is one of our key partners, but the portion Meta represents has been shrinking over recent years as we purposefully diversify our channel mix with many other partners. To give an example, we leverage an affiliate partner network of 100+ partners across 20+ countries. No single channel dominates because no single channel should. Our channel mix is indication- and geography-led, not platform-led. We use every channel that works for the patient population in question, optimized continuously through data, and we are transparent with clients on where their media investment is going and what it is returning.
Sites have competing priorities and different levels of resources, what we control is how actively we support them, how visible the referral pipeline is, and how quickly we spot a site falling behind, so we can intervene.
We maintain a consistent site opt-in rate of around 70-80%, and boast a site satisfaction score of 80%. We request that sites process referrals within 3-5 working days, and support this through our dedicated site support team and escalation processes. This keeps referrals moving and ensures our customers’ investments yield returns.
What clients should push us on: Ask for site activation timelines, average time from referral to first contact, and dropout rates between referral and screening visit by study. Those three numbers tell you more about funnel health than any headline metric we could quote, and they’re exactly what our site partnership team tracks daily, escalating any site that falls behind.
Security and compliance are non-negotiable for us, as they should be for any vendor handling patient data at this scale. We welcome scrutiny, and we support client audit processes as a standard part of how we work together.
Clariness has operated across 60+ countries for over two decades, which means navigating GDPR in Europe, HIPAA in the US, and a complex web of local data residency and compliance requirements across Asia Pacific, Latin America, and beyond. We have very strict data privacy processes in place and build our processes on European data privacy principles, as they are among the diligent regulations in the world. Data security and patient privacy are not bolt-ons; they are built into how the platform operates.
Patient data is never sold, shared, or used for purposes outside the specific study the patient consented to. Consent management is built into the patient journey at every touchpoint. Data residency requirements are respected by geography, meaning patient data stays where it is required to stay. Access controls, encryption and audit trails are standard across both platforms.
The ClinLife® platform as an example is SOC2 Type II certified and strictly audited by our internal compliance team for standard regulatory requirements like ISO, HIPAA and GCP where applicable.
We believe clients should have the same visibility of recruitment performance as we do, in real time, without friction (and without any personally identifiable patient data of course). That level of transparency is part of how we hold ourselves accountable to the outcomes we have committed to deliver.
One of the most consistent complaints sponsors and CROs have with other recruitment vendors is that performance data arrives late, lives in multiple systems, or requires a weekly call to interpret. We are built to fix that and provide data in any format that fits the customer’s environment, be it a business intelligence report or an API interface. Our platforms give clients 24/7 data access to all relevant recruitment details for all their studies, down to single referral, country, and site level.
The Clariness Hub provides real-time campaign dashboards covering patient engagement, funnel progression, site activity, and referral volumes by geography and indication. Clients can see where patients are dropping out, which channels are performing, and which sites are converting, without waiting for a report. Clients should expect visibility on referral volumes and quality, time from referral to site contact, screen failure rates by site and geography, enrolment velocity against target, and cost per outcome at each funnel stage. All of it updated in real time, all of it accessible without needing to chase an account manager or a project manager for a spreadsheet.
What is coming with ARIA: The Analytics Intelligence Agent is specifically designed to go beyond dashboards. Rather than presenting data and leaving interpretation to the client, ARIA allows business users to ask questions of the data directly, validate KPIs instantly, and surface insights that would previously have required a data team request. Proposal preparation, performance reviews, and mid-study optimization decisions all become faster and more confident.
Historically, we have seen that patients do not respond to pharma brands the way sponsors hope they will. First of all, patients are not searching for a specific sponsor, but for their indication or disease area. Decades of research and millions of patient interactions tell us that when a patient sees a pharmaceutical company name on a recruitment landing page, trust goes down and drop-off goes up. Patients associate pharma brands with commercial interests, not with their own health journey. ClinLife® works because it is perceived as a neutral, patient-first platform, not an ad for a drug. Patients trust a sponsor-neutral brand like ClinLife® a lot more, and we see higher conversion rates using our end-to-end process.
What ClinLife® actually represents to patients: Over 15 million patients visit ClinLife® annually because they trust it as a place to find trials relevant to their condition. That trust has been built over 20 years, and it is not transferable to a sponsor brand overnight. When a patient lands on a ClinLife®-branded page, they are in a familiar, credible environment. That familiarity directly improves conversion rates, consent rates, and ultimately randomization numbers.
What sponsors actually get: The study, the protocol, the sites and the outcomes are all yours. The branding of the patient-facing journey is optimized for patient behavior, not sponsor visibility. These are two different things, and conflating them costs enrolment performance.
We are not one-size-fits-all on this: We recognize that some sponsors have built genuine patient communities and condition-specific brands that patients already trust. In those cases, we offer co-branded and white-label options within the platform, so the patient experience reflects both the sponsor’s brand equity and the credibility of the ClinLife® environment. It is a conversation we welcome early in the study setup process.
But we lead with the evidence: For sponsors who want to see the data before making that call, we can show conversion rate comparisons between sponsor-branded and platform-branded patient journeys across comparable studies and indications. In many cases, the numbers make the argument more convincingly than we ever could. Patients convert better when they feel they are making a personal health decision, not responding to a pharmaceutical campaign.
The practical offer: Three options on the table for every client. Full ClinLife® branding for maximum conversion performance. Co-branded experience where sponsor identity and ClinLife® credibility sit alongside each other. White label for sponsors with established patient communities where their own brand demonstrably drives trust. We recommend based on the data and the indication, not on a default position, and we are transparent about the trade-offs of each approach.
The short answer: Because we do not stop at the referral. Most vendors measure success at the top of the funnel. We measure it at randomization, and we have built everything in the ClinLife® platform and the processing around that single outcome, “”Consented Patients””, not as an afterthought of the recruitment funnel.
The full funnel difference: Getting a patient to raise their hand is the easy part. Converting that interest into a screened, consented, and randomized participant is where most recruitment programs fall apart, and where most vendors quietly step back. Our Enrollment Enablement Team sits in the middle of that gap, actively managing patients through every step in their local language, at the right time, through the right channel.
Simplified pre-screening: Medical eligibility questions written in plain patient language, not protocol copy. Patients understand what is being asked, qualify themselves accurately, and arrive at sites better prepared. Fewer screen failures, less wasted time on both sides. Screening can be done on either program or protocol level, reducing failures to be moved across studies.
Virtual Waiting Room: For studies with flare conditions, we keep the patients in VWR, rescreen them, and in cases even relocate them as appropriate, reducing further dropped patients. This is also applicable when a site reaches capacity, thereby preventing patients held up in non-performing sites.
Predictive funnel management: Statistically-backed models that forecast enrolment velocity, identify drop-off risk early and trigger intervention before a patient gets cold. We do not wait for a site to flag a problem; we see it coming.
Screening failure feedback loop: Every screen failure is captured, categorized, and fed back into the screening model. Over time, this continuously sharpens eligibility criteria, improves pre-screening accuracy, and reduces the rate of unqualified patients reaching sites. The platform gets smarter with every study, and every failure becomes an input that improves the next one.
Geo-fencing: As site activation scales, our campaign targeting tightens around active sites automatically. Media spend follows site readiness, not the other way around, so we are never generating patients for sites that cannot receive them yet.
Warm transfer: Rather than sending a referral and hoping the site calls, we bridge the patient directly to the scheduling team in real time. One connected conversation, no cold handoff, significantly higher booking rates.
Medical record integration: Longitudinal patient history surfaced at the point of referral, with patient consent, so sites can assess eligibility before the first appointment. Patients who are a strong match are prioritized, so site capacity is reserved for those most likely to benefit.
Simpler site portal and API integration: A single interface for sites to manage referrals, track patient status and access performance data, with API connectivity into existing site systems to reduce administrative burden and keep teams focused on patient care.
The result: More qualified patients, better prepared sites, fewer drop-offs and faster time to consent/randomize. That is why the number is 42,000+ and counting.
Where we are today: Two of the strongest patient outreach systems in the industry, now operates under one enrollment ecoystem, powered by ClinLife®. We welcome 15 million+ annual visitors and leverage 20 years of condition-specific patient communities combined with Subject Well’s patient communities, digital media networks, and US-market channel depth. The starting point is already stronger than most competitors can match individually.
What will come: We built our outreach ecosystem to be self-improving. Every patient interaction, every screen failure, and every successful randomization feeds back into the targeting models, the messaging frameworks, and the channel allocation decisions. The continuous measuring and optimizing of every enrollment funnel helps us in reaching patients at precisely the right moment, in the right language, through the right channel, without requiring manual intervention at every touchpoint. Moving further along the funnel, our team focuses on complex cases, site relationships, and strategic decisions rather than routine follow-up. Outreach stops being a campaign and becomes a continuous, intelligent conversation with the right patient populations at global scale.
What we will retain: Patient trust is the foundation everything at Clariness is built on. Every evolution of the outreach ecosystem will be evaluated against one question: does it strengthen or weaken the trust that makes patients engage with us? Conversion optimization that damages patient experience is not a trade-off we are willing to make, this ethos backs our solutions being built for outcomes, not optics.
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